不锈钢自动超滤系统

Stainless Steel Automatic Ultrafiltration System

The stainless steel automatic ultrafiltration system is primarily composed of a utility unit, stainless steel ultrafiltration tank unit, ultrafiltration piping unit, and control unit. It can meet the diverse functional needs of different customers for various products. Additionally, Lecheng can provide multiple instrument options and customized designs.

The stainless steel automatic ultrafiltration system is suitable for laboratory, pilot-scale, and production-scale applications. Furthermore, the system can be used in conjunction with internationally branded membrane cassettes or hollow fiber products.

Typical Applications

Application Fields: Antibodies, blood products, vaccines, recombinant proteins, liposomes, small molecules (insulin, peptides, polysaccharides, monosaccharides, etc.), novel therapies (plasmids, viral vectors, etc.), traditional Chinese medicine injections, chemical drugs.

Concentration: Concentration of biological macromolecules

Dialysis: Diafiltration, desalting, de-alcoholization, buffer exchange

Molecular Weight Cut-off: Small molecules pass through the membrane, while large molecules are retained

Endotoxin Removal: Product passes through the membrane, while pyrogens are retained

Product Advantages

Extremely low holdup volume, enabling maximum product recovery rate

Automatic control of transmembrane pressure (TMP) / differential pressure (DP)

Formula-based management, offering flexible operation

Control system complies with GAMP5 and 21CFR PART11

Simple operation interface, stable control system

Compact design, occupying minimal space

Modular design, allowing equipment to be fixed or freely movable

Customized multifunctional design

Optional online monitoring of pH, conductivity, UV, etc.

Technical Parameters

All wetted parts, including pipes and valves, are made of 316L stainless steel, with an electropolished finish of 0.4μm.

Power requirement: 220VAC or 380VAC, 50Hz

Instrument air requirement: 6-8 bar

Process air requirement: 2 bar

Cleaning water source requirement: 1.5 bar

Software features include permission management, audit trail, data storage and backup, electronic signatures, alarms, recipe management, domain control management, batch reporting, etc.

Technical Parameters

不锈钢自动超滤系统

不锈钢自动超滤系统主要由公用工程单元、不锈钢超滤罐单元、超滤管路单元及控制单元组成。可满足不同客户对不同产品的多种功能性需求，同时乐纯还可以提供多种仪表的选配及定制化设计。

不锈钢自动超滤系统适用于实验室、中小试及生产规模的产品。同时，系统可搭配国际品牌的膜包或中空纤维产品配套使用。

典型应用

应用领域：抗体、血液制品、疫苗、重组蛋白、脂质体、小分子（胰岛素，多肽，多糖，单糖等）、新型治疗（质粒，病毒载体等）、中药注射剂、化药。

浓缩：生物大分子浓缩

透析：洗滤、脱盐、脱醇、缓冲液置换

分子量切割：小分子透过膜，大分子被截留

除内毒素：产品透过膜，热源被截留

产品优势

极低的滞留量，可实现最大的产品回收率 .      

跨膜压TMP/压差DP的自动控制

配方式管理，操作比较灵活

控制系统满足GAMP5，21CFR PART11

操作界面简单，控制系统稳定

设计紧凑，占用空间小

模块化设计，设备可固定或自由移动

定制化多功能设计

可选配在线监测pH、电导率、UV等

技术参数

与料液接触的管件和阀门等部件均为316L不锈钢材质，电抛0.4μm电源需求：220VAC或380VAC，50Hz

仪表压空需求：6-8bar

工艺压空需求：2bar

清洗水源需求：1.5bar

软件功能包含权限管理、审计追踪、数据存储备份、电子签名、报警、配方管理、域控管理、批报表等

技术参数